Microflow system promotes acetaminophen crystal nucleation
نویسندگان
چکیده
منابع مشابه
Crystal Nucleation without Supersaturation.
Classical nucleation theory (CNT) has been extensively employed to interpret crystal nucleation phenomena and postulates the formation of an ordered crystalline nucleus directly from vapor or solution. Here, we provide the first experimental demonstration of a two-step mechanism that facilitates deposition of crystals on solid surfaces from vapor. Crucially, this occurs from saturated vapor wit...
متن کاملCharacterizing Protein Crystal Nucleation
Characterizing Protein Crystal Nucleation A dissertation presented to the Faculty of the Graduate School of Arts and Sciences of Brandeis University, Waltham, Massachusetts by Sathish V. Akella We developed an experimental microfluidic based technique to measure the nucleation rates and successfully applied the technique to measure nucleation rates of lysozyme crystals. The technique involves c...
متن کاملRadical carbonylations using a continuous microflow system
Radical-based carbonylation reactions of alkyl halides were conducted in a microflow reactor under pressurized carbon monoxide gas. Good to excellent yields of carbonylated products were obtained via radical formylation, carbonylative cyclization and three-component coupling reactions, using tributyltin hydride or TTMSS as a radical mediator.
متن کاملTe nucleation and crystal growth
The nucleation and growth of Cd 1~x Zn x Te crystals in a multi-zone vertical Bridgman growth furnace have been observed and measured using in situ eddy current sensor techniques. A two-coil eddy current sensor measured coil impedance changes for multifrequency which were then interpreted using an electromagnetic "nite element analysis. The sensor was used to characterize the initial melting of...
متن کاملMetadynamics studies of crystal nucleation
Crystallization processes are characterized by activated events and long timescales. These characteristics prevent standard molecular dynamics techniques from being efficiently used for the direct investigation of processes such as nucleation. This short review provides an overview on the use of metadynamics, a state-of-the-art enhanced sampling technique, for the simulation of phase transition...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Engineering in Life Sciences
سال: 2020
ISSN: 1618-0240,1618-2863
DOI: 10.1002/elsc.202000021